Description
Product Overview: AOD-9604
AOD-9604 (Advanced Obesity Drug 9604) is a synthetic 16-amino acid peptide fragment derived from the C-terminal region of human growth hormone (specifically hGH 176–191) with an added N-terminal tyrosine residue for enhanced molecular stability. Originally engineered to isolate the metabolic and fat-reducing properties of full-length growth hormone, AOD-9604 mimics the lipolytic action of hGH without inducing systemic anabolic, growth-promoting, or diabetogenic side effects.
Primary Research Applications & Reasons for Study
- Targeted Lipolysis: Accelerating the enzymatic breakdown of stored triglycerides into free fatty acids in localized adipose tissue models.
- Lipogenesis Inhibition: Suppressing key lipogenic pathways (such as acetyl-CoA carboxylase activity) to prevent the formation and accumulation of new fat deposits.
- Metabolic & Glucose Safety: Evaluating growth hormone-like metabolic benefits without inducing insulin resistance, hyperglycemia, or IGF-1 elevation.
- Cartilage & Joint Repair: Investigating secondary regenerative pathways that support chondrocyte proliferation and proteoglycan synthesis in joint tissue models.
Expected Research Results & Timeline Metrics
- Phase 1 / Days 1–7
Initial Metabolic Activation: Early biological shifts show increased upregulation of beta-3 adrenergic receptors and elevated free fatty acid mobilization in localized fat stores. - Phase 2 / Weeks 2–4
Measurable Adipose Reduction: Statistically significant reductions in regional fat mass and lipid droplet density within experimental cell cultures and animal models. - Phase 3 / Weeks 4–8
Sustained Compositional Shifts: Marked shifts in overall body composition parameters, steady suppression of lipogenic enzymes, and enhanced cartilage repair markers in joint inflammation models—all while maintaining stable baseline blood glucose and insulin levels.
Key Research Benefits
- Direct Fat Breakdown: Stimulates lipolysis directly in white adipose tissue without relying on systemic thyroid or adrenal stimulation.
- Inhibition of Fat Storage: Blocks lipogenesis, effectively preventing pre-adipocytes from maturing into fully stored fat cells.
- GH-Independent Safety Profile: Bypasses classical hGH receptors, avoiding unwanted organ growth, fluid retention, or structural bone enlargement.
- Connective Tissue Support: Demonstrates potential regenerative synergy when evaluated in cartilage, tendon, and joint repair models.
THIS PRODUCT IS INTENDED SOLELY FOR IN VITRO LABORATORY RESEARCH AND EXPERIMENTAL PURPOSES. It is strictly prohibited for human consumption, clinical trials, therapeutic administration, cosmetic use, or veterinary application. This product is not an FDA-approved drug, medical food, or dietary supplement. It is not intended to diagnose, treat, cure, or prevent any disease, illness, or medical condition. Any handling, reconstitution, or experimentation involving this chemical compound must be conducted strictly by qualified, trained laboratory professionals utilizing appropriate containment and personal protective equipment in accordance with scientific biosafety standards. Buyers and users assume full liability for compliance with local, state, and federal laws regarding the handling and possession of research peptides.